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Tethered cord syndrome (TCS) or occult spinal dysraphism sequence refers to a group of neurological disorders that relate to malformations of the spinal cord.〔(Tethered Spinal Cord ), Columbia University Department of Neurosurgery〕 Various forms include: * Tight filum terminale * Lipomeningomyelocele * Split cord malformations (diastematomyelia) * Dermal sinus tracts * Dermoids * Cystoceles.〔 All forms involve the pulling of the spinal cord at the base of the spinal canal, literally a ''tethered cord''.〔 The spinal cord normally hangs loose in the canal, free to move up and down with growth, and with bending and stretching. A tethered cord, however, is held taut at the end or at some point in the spinal canal. In children, a tethered cord can force the spinal cord to stretch as they grow. In adults the spinal cord stretches in the course of normal activity, usually leading to progressive spinal cord damage if untreated.〔 TCS is often associated with the closure of a spina bifida. It can be congenital, such as in tight filum terminale, or the result of injury later in life. ==Signs and symptoms== In children, symptoms may include: *Lesions, hairy patches, dimples, or fatty tumours on the lower back * Foot and spinal deformities * Weakness in the legs〔 * Change in or abnormal gait including awkwardness while running or wearing the tips or side of one shoe〔 * Low back pain〔 * Scoliosis〔 * Urinary irregularities (incontinence or retention)〔 Tethered spinal cord syndrome may go undiagnosed until adulthood, when sensory, motor, bowel, and bladder control issues emerge. This delayed presentation of symptoms relates to the degree of strain on the spinal cord over time. Tethering may also develop after spinal cord injury. Scar tissue can block the flow of fluids around the spinal cord. Fluid pressure may cause cysts to form in the spinal cord, a condition called syringomyelia. This can lead to additional loss of movement or feeling, or the onset of pain or autonomic nervous system symptoms. In adults, onset of symptoms typically include: * Severe pain (in the lower back and radiating into the legs, groin, and perineum) * Bilateral muscle weakness and numbness * Loss of feeling and movement in lower extremities * Urinary irregularities (incontinence or retention) * Bowel control issues Neurological symptoms can include a mixed picture of upper and lower motor neuron findings, such as amyotrophy, hyperreflexia, and pathologic plantar response, occurring in the same limb. Profound sensory changes, such as loss of pain, temperature, and proprioceptive sensations, are common. Last, progressive symptoms of a neuropathic bladder are noted on over 70% of adult patients, versus only 20% to 30% of children. These symptoms include urinary frequency and urgency, feeling of incomplete voiding, poor voluntary control, and urge and stress incontinence. Chronic recurrent infections are common and occasionally lead to nephrolithiasis (kidney stones), renal failure, or renal transplantation. Female patients also give a history of ineffective labor and postpartum rectal prolapse, presumably due to an atonic pelvic floor. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tethered spinal cord syndrome」の詳細全文を読む スポンサード リンク
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